姓名：王华峰

专业：免疫学

研究领域：基础医学

联系方式：电话：17636217979；邮箱：wanghf@sxnu.edu.cn

个人简介：

王华峰，男，副教授，硕士生导师。医学博士。从事基础医学，侧重于治疗改善疾病的植物生物活性成分的开发与利用，涉及免疫炎症、肝损伤修复机制、肿瘤等方面的研究。

教育背景：

2011.09-2014.07，博士，免疫学，天津医科大学

2001.09-2004.10，硕士，果树学，南京农业大学

1991.09-1995.07，学士，果树学，南京农业大学

国际交流

2019.02-2022.10 阿拉巴马大学伯明翰分校的医学院（美），访问学者

科研项目：

1.中央引导地方科技发展资金：谷子多酚靶向TGF-β1蛋白改善胃癌的分子机制研究，研究周期为2024年12月-2027年12月，担任项目子课题负责人。

学术论文：

1. Huafeng Wang, Huan Zhang , Yanxia Wang, Luhong Yang, Dong Wang. Embelin can protect mice from thioacetamide-induced acute liver injury [J]. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, 118: 109360.

2. Huafeng Wang, Huan Zhang, Biao Huang, Guolin Miao, Xiaoyan Yan, Gang Gao, Yongping Luo, Huize Chen, Wei Chen, Luhong Yang, Mesenchymal stem cells reverse high-fat dietinduced nonalcoholic fatty liver disease through suppression of CD4+ T lymphocytes in mice, Molecular medicine reports, 2018, 17(3): 3769-3774

3. Wang Huafeng, Wang Dong, Yang Luhong, Wang Yanxia, Jia Junli, Na Dongchen, Chen Huize, Luo Yongping, Liu Chengfang. Compact bone-derived mesenchymal stem cells attenuate nonalcoholic steatohepatitis in a mouse model by modulation of CD4 cells differentiation [J]. Int Immunopharmacol, 2017, 42: 67-73.

4. Huafeng Wang, Luhong Yang, Wang Dong, Zhang Qi, Lijuan Zhang. Pro-tumor activities of macrophages in the progression of melanoma [J]. Human Vaccines & Immunotherapeutics, 2017 (2) :1556-1562.

5. Huafeng Wang, Huan Zhang, Zimu Zhang, Biao Huang, Xixi Cheng, Dan Wang, Zha la Gahu, Zhenyi Xue, Yurong Da, Daiqing Li, ZhiYao, Fei Gao, Aimin Xu*, Rongxin Zhang*, Adiponectin-derived active peptide ADP355 exerts anti-inflammatory and anti-fibrotic activities in thioacetamide-induced liver injury, Scientific reports, 2016, 6: 19445

6. Chao Li, Zhong Liu, Xiaoxia Zhang, Huafeng Wang, Gregory K Friedman, Qiang Ding, Xinyang Zhao, Hu Li, Kitai Kim, Xi Yu, L Burt Nabors, Xiaosi Han, Rui Zhao. Generation of chromosome 1p/19q co-deletion by CRISPR/Cas9-guided genomic editing. Neurooncol Adv, 2022. 4(1): p. vdac131.

7. Pulin Che, Lei Yu, Gregory K Friedman, Meimei Wang, Xiaoxue Ke, Huafeng Wang, Wenbin Zhang, Burt Nabors, Qiang Ding, Xiaosi Han. Integrin αvβ3 Engagement Regulates Glucose Metabolism and Migration through Focal Adhesion Kinase (FAK) and Protein Arginine Methyltransferase 5 (PRMT5) in Glioblastoma Cells. Cancers (Basel), 2021. 13(5).

8. Lijuan Zhang, Kai Zhang, Jieyou Zhang, Jinrong Zhu, Qing Xi, Huafeng Wang, Zimu Zhang, Yingnan Cheng, Guangze Yang, Hongkun Liu, Xiangdong Guo, Dongmei Zhou, Zhenyi Xue, Yan Li, Qi Zhang, Yurong Da, Li Liu, Zhinan Yin, Zhi Yao, Rongxin Zhang. Loss of fragile site-associated tumor suppressor promotes antitumor immunity via macrophage polarization. Nat Commun, 2021. 12(1): p. 4300.

学术著作：

1.《遗传学实验》，科学出版社，2010.12（主编）

2. 沪科教版新课标高中生物-必修2(遗传与进化)，参与编写

承担教学：

1.本科生课程：遗传学及实验、免疫学

2.研究生课程：遗传学及表观遗传学的研究进展

合作意向：

1.企业合作案例

2.可承接科研任务

3. 科技服务经历