魏作富

姓名:魏作富
专业:植物学
研究领域:植物次生代谢物及其生物活性和调控
联系方式:电话:17835050397;邮箱:zorff@163.com
个人简介:
魏作富,男,副教授,硕士生导师。植物学博士,中国化学学会员。主要围绕植物次生代谢物开展研究:(1)植物活性物质基础;(2)植物活性成分作用机制;(3)植物次生代谢物的调控。主持或参与中央引导地方科技发展资金项目、山西省基础研究计划项目、国家自然科学基金、科技部农业科技成果转化资金项目等项目;以第一作者和通讯作者身份在Journal of Agricultural and Food Chemistry、Chemical Engineering Journal、Industrial Crops and Products、Separation and Purification Technology等领域内权威期刊发表论文近20篇。以主要发明人申请国家专利8项,授权5项。
教育背景:
2012.09-2015.06,博士,植物学,东北林业大学
2009.09-2012.06,硕士,生药学,东北林业大学
2005.09-2009.07,学士,生物科学,东北林业大学
工作经历:
2018.01-至今,副教授,山西师范大学生命科学学院
2015.07-2017.12,讲师,山西师范大学生命科学学院
科研项目:
1.山西省基础研究计划,基于NF-κB抑制作用的柳叶鼠李叶抗神经炎症成分及其作用机制研究(项目编号:20210302123328),2022-2024,主持
2.山西省应用基础研究项目,柳叶鼠李叶适茶性研究(项目编号:201701D221246),2017-2019,主持
3.山西省高等学校科技创新项目,柳叶鼠李叶抗菌研究(项目编号2020L0236),2020-2022,主持
4.中央高校基本科研业务费专项资金项目,犬问荆抗幽门螺杆菌活性成分及其作用机制研究(项目编号2572014AA02),2014-2015,主持
5.中央引导地方科技发展资金项目,柳叶鼠李叶功能成分对阿尔茨海默病的保护作用及机制研究(项目编号:YDZJSX2024D059),2024-2026,参与
6.国家自然科学基金青年项目,miR-148b在奶牛乳腺发育与泌乳调节中的功能及作用机制研究(项目编号31701118),2018-2020,参与
7.科技部农业科技成果转化资金项目,黄芪资源精深加工关键技术中试与示范(项目编号2012GB23600641),2012-2014,参与
8.科技部农业科技成果转化资金项目,木豆叶活性成分高效诱导提取分离技术中试与示范(项目编号2009GB23600514),2009-2011,参与
9.国家林业局引进国际先进林业科学技术项目,特异性木豆内生真菌生产木豆芪酸技术引进(项目编号2012-4-06),2012-2014,参与
学术论文:
1.Biotransformation of Bioactive Metabolites in Cassiae Semen by Endogenous Enzymes and Probiotic. Journal of Agricultural and Food Chemistry, 202472, 5293-5306.
2.Anti-neuroinffammatory effect of ombuin from Rhamnus erythroxylon Pall. leaves in LPS-induced BV-2 microglia by targeting Src and suppressing the PI3K-AKT/NF-κB signaling pathway. International Journal of Molecular Sciences, 2024, 25, 8789.
3.Evaluation of nutritional value, bioactivity and mineral content of quinoa bran in China and its potential use in the food industry. Current Research in Food Science, 2023, 7, 100562.
4.Optimization of Aqueous Enzymatic Microwave Assisted Extraction of Macadamia Oil And Evaluation of Its Chemical Composition, Physicochemical Properties, and Antioxidant Activities. European Journal of Lipid Science and Technology, 2022, 124, 2100079.
5.Dual-cooled solvent-free microwave extraction of Salvia officinalis L. essential oil andevaluation of its antimicrobial activity. Industrial Crops and Products. 2018, 120, 71-76.
6.Geraniin exerts cytoprotective effect against cellular oxidative stress by upregulation of Nrf2-mediated antioxidant enzyme expression via PI3K/AKT and ERK1/2 pathway. Biochimica et Biophysica Acta (BBA) - General Subjects. 2015, 1850, 1751-1761.
7.Application of natural deep eutectic solvents for extraction and determination of phenolics in Cajanus cajan leaves by ultra performance liquid chromatography. Separation and Purification Technology, 2015, 149, 237-244.
8.Fast and green extraction and separation of main bioactive flavonoids from Radix Scutellariae. Industrial Crops and Products, 2015, 63, 175-181.
9.Equisetumone, a novel 4-5-olide secocaryophyllane sesquiterpene from Equisetum palustre. RSC Advances, 2014, 4, 45749-45752.
10.Simultaneous determination of phenolic compounds in Equisetum palustre L. by ultra performance liquid chromatography-tandem mass spectrometry combined with matrix solid-phase dispersion extraction. Journal of Separation Science, 2014, 37, 3045-3051.
11. Variation in Contents of Main Active Components and Antioxidant Activity in Leaves of Different Pigeon Pea Cultivars during Growth. Journal of Agricultural and Food Chemistry, 2013, 61, 10002-10009.
12.UV-Induced Changes of Active Components and Antioxidant Activity in Postharvest Pigeon Pea [Cajanus cajan (L.) Millsp.] Leaves.Journal of Agricultural and Food Chemistry , 2013, 61, 1165−1171.
13.An efficient preparative procedure for main flavone aglycones from Equisetum palustre L. using macroporous resin followed by gel resin flash chromatography.Separation and Purification Technology, 2013, 118, 680-689.
14.Resin adsorption as a means to enrich rare stilbenes and coumarin from pigeon pea leaves extracts. Chemical Engineering Journal, 2011, 172, 864-871.
15. Negative-pressure cavitation extraction of cajaninstilbene acid and pinostrobin from pigeon pea [Cajanus cajan (L.) Millsp.] leaves and evaluation of antioxidant activity. Food Chemistry, 2011, 128, 596-605.
16.犬问荆化学成分研究. 中药材, 2021, 2, 335-339.
承担教学:
1.本科生课程:植物学(上)、植物学实验(上)
2.研究生课程:植物学研究专题
获奖:
1.木豆资源功能活性成分高值化加工利用关键技术及产业化应用,黑龙江省科学技术发明奖一等奖, 2017
2.高原特色植物资源发掘及功能性成分开发,中国侨界贡献奖(创新团队), 2016
3.北药黄芪生态培育与高效加工技术集成,黑龙江省高校科学技术奖一等奖,2014
专利:
1.一种中药蒸馏提取装置, CN 221358564 U
2.一种具有温控功能的中药发酵设备, CN 221566100 U
3.一种从大青叶中分离纯化(+)-异落叶松树脂醇和(-)-落叶松脂素的方法,ZL 201210379454.5
4.一个芪类活性成分及其制备方法与应用,ZL 201110423178.3
5.一种新的倍半萜活性成分及其制备方法与应用,ZL201310063103.8
合作意向:
1. 可承接科研任务:围绕中药材或药食同源植物种质选育和评价、功能成分或产品的应用开发。
一审:段雅婷
二审:张杰
三审:郭飞


